Laboratory Products
Microlitre Flow Calorimeter
May 09 2012
Enhance enzyme discovery and optimisation with the new chipCAL, a low cost, low volume flow calorimeter from TTP Labtech. Its fast throughput enables characterisation of enzyme activity to be achieved within 2-10 minutes per sample, thus opening the door to high-throughput enzyme screening, said the company. In addition, chipCAL is suitable for monitoring a range of processes in the biopharma, food and fermentation industries. ChipCAL’s technology employs a flow principle, thereby enzyme and substrate are passed through a thermodynamic cell simultaneously. This allows chipCAL to detect thermodynamic changes using volumes as low as 15μL, minimising the amount of valuable sample used per analysis. chipCAL’s microliter flow calorimetry also provides the additional benefit of non-contact, label-free sample monitoring. Dr Marcel van Tilborg, Corporate Scientist, DSM Biotechnology Centre, who has been closely involved in pilot studies using chipCAL said “finally it is possible to achieve fast, labelfree and absolute activity measurements - a breakthrough for everyone using enzymes who need speed, accuracy and low cost in biological assays."
Easy to use chipCAL has a wide working temperature range of between 15°C-60°C, allowing a broad variety of biological activities to be analysed. Following analysis, samples are simply passed through to a waste unit and a new sample can be loaded, without the need for a laborious wash stage. This technology has the potential to significantly enhance high-throughput enzyme screening, being capable of analysing up to 60 samples in an 8 hour working day.
Digital Edition
International Labmate 49.6 - Sept 2024
September 2024
Chromatography Articles - HPLC gradient validation using non-invasive flowmeters Mass Spectrometry & Spectroscopy Articles - From R&D to QC, making NMR accessible for everyone: Putting NMR...
View all digital editions
Events
Oct 20 2024 Fort Worth, TX, USA
Oct 21 2024 Dalian, China
Oct 30 2024 Birmingham, UK
Oct 30 2024 Manchester, UK
Nov 11 2024 Dusseldorf, Germany