Innovative Minibioreactors Allows Multiple Simultaneous Cell Culture Trials

Telstar is introducing into the market a completely innovative minibioreactor model to perform animal cell culture screening studies on a scale applicable to R&D. Planned for March 2010, this equipment will be launched on the market under the brand name of Telstar Hexascreen.It is the first minibioreactor on the market to enable animal cell culture trials and experiments on a scale of 10 to 15m, with the capacity to handle six cultures at a time, and a workstation accommodating single-use interchangeable plates to guarantee sterility and speed up the start of the bioprocess. These units offer change of medium, monitoring and control facilities, which enable the collection of information on the main culture variables, such as the temperature, dissolved oxygen/oxygen consumption, pH, optical density and measurement of the spectrum in the visible range, while simultaneously monitoring growth (absorbance) and metabolism (indirectly from acidification/ oxygen consumption).

All these features make the Telstar Hexascreen the most innovative equipment for the pharmaceutical and biotechnology industry market because it speeds up the bioprocess and multiples the opportunities for experimentation by being able to develop six simultaneous cultures and it facilitates the start of the bioprocess by the use of replaceable plates which ensure sterility, requiring the user merely to inoculate the cultures before placing the plate in the workstation. This innovation overcomes the complexity of use usually found in bioreactors, which involve laborious preparation, sterilisation and calibration processes before the start of the cultures, often requiring highly qualified personnel. During 2010, Telstar will develop a new stage in the Telstar Hexascreen minibioreactor by incorporating the fed-batch model for growth and increased productivity of the cell culture.