• Culturing clinical grade iPSC’s with StemFit® Basic03.
  • iPS-Cell Based Cell Therapies for Genetic Skin Disease
    EB patient derived iPS-cells that were reprogrammed from primary fibroblast cell samples and will be expanded for genetic correction.
  • Culturing clinical grade iPSC’s with StemFit® Basic03.
  • iPS-Cell Based Cell Therapies for Genetic Skin Disease
    EB patient derived iPS-cells that were reprogrammed from primary fibroblast cell samples and will be expanded for genetic correction.

Laboratory products

iPS-Cell Based Cell Therapies for Genetic Skin Disease

AMSBIO has published an interview with Professor Marius Wernig from Stanford University, Pathology Stem Cell Institute that discusses what could be the world’s first widely applicable curative treatment for Epidermolysis Bullosa (EB).

This rare genetic disease causes chronic and incredibly painful skin wounds that often lead to an aggressive form of skin cancer and eventual death.

While various cell-therapy approaches have been attempted, Professor Wernig and collaborators identified the need for induced pluripotent stem cells (iPSCs), and how they could become used to treat EB in a more efficient, applicable, and commercially viable manner.

In the past, the only way Professor Wernig’s research group could grow iPSCs cells with a normal karyotype over longer periods of time was on mouse feeder cells with serum. This combination of mouse cell co-culture and undefined bovine serum set was not a suitable methodology as it was almost impossible to perform in compliance with FDA safety standards.

Professor Wernig describes how StemFit® Basic03 clinical grade stem cell culture medium, available from AMSBIO has allowed his research group to safely expand their cells using an FDA compliant protocol. While there are still hurdles to climb before a cure for EB is fully realised, using StemFit® Basic03 has solved the challenge of reproducibly growing clinical grade iPSC’s.

Read the full interview.

Completely free of animal- and human-derived components StemFit® Basic03 provides highly stable and reproducible culture condition for Induced Pluripotent Stem and Embryonic Stem cells under feeder-free conditions during the reprogramming, expansion, and differentiation phases of stem cell culture. StemFit® Basic03 combines high colony forming efficiency with lower than standard media volume consumption to offer cost effective colony expansion when compared to leading competitors.

More information online


Digital Edition

Lab Asia 32.1 Feb 2025

February 2025

Chromatography Articles - Comparing volumetric and thermal flowmeters for assessing and validating liquid chromatography performance Mass Spectrometry & Spectroscopy Articles - The importa...

View all digital editions

Events

SPS Smart Production Solutions Guangzhou

Feb 25 2025 Guanghzou, China

SmartLab Exchange

Feb 25 2025 Amsterdam, Netherlands

Nepal Lab

Feb 27 2025 Kathmandu, Nepal

PITTCON 2025

Mar 01 2025 Boston, MA, USA

IFPAC 2025

Mar 02 2025 Bethesda, MD, USA

View all events

Redirecting you now.
Labmate Awards Nominations - Open
The Labmate Awards for Excellence 2025 seek to recognise innovation, quality and achievement wherever it occurs within the laboratory sector. Launching this year the Labmate Awards for Excellence 2025 will have eleven voting categories chosen to reflect the broad range of noteworthy contributions that have been made across our industry in the past 12 months. Nominate your company Now.