Extended pH Stability ACE SuperC18 Ultra-Inert UHPLC and HPLC Columns

ACE SuperC18 Ultra-inert UHPLC/HPLC columns from Advanced Chromatography Technologies offer excellent stability across an extended pH range (pH 1.5 to 11.5), allowing chromatographers to routinely exploit beneficial selectivity changes at low, intermediate and high pH. ACE SuperC18 columns can be used with both MeOH and MeCN mobile phases and offer rapid column equilibration without memory effects. They are designed for use with LC/MS compatible buffers and offer ultra-low bleed for improved LC/MS compatibility. 2µm, 3µm and 5µm analytical columns are supplied in dual compatible UHPLC/HPLC Excel hardware and are stable up to pressures of 1,000bar/15,000psi. A 10µm particle size is also available.

A wide range of preparative column dimensions enables reproducible scale up from analytical dimensions and allows chromatographers to explore the opportunity of increased loading capacity at elevated pH.

ACE SuperC18 columns feature proprietary “Encapsulated Bonding Technology” which dramatically increases the ligand coverage of the silica surface and effectively eliminates the effect of unbonded silonol groups from separations. This higher ligand coverage results in improved inertness, chromatographic performance and stability.

ACE SuperC18 Ultra-Inert UHPLC and HPLC Columns with Extended pH Stability:-

1.  An ideal choice for method development

• Exploit selectivity changes at low, intermediate and high pH
• Excellent column lifetime for reduced analysis cost

2.  Specially designed for high and low pH mobile phases

• Designed for use with LC/MS compatible buffers
• Recommended pH range 1.5 – 11.5

3.  Ultra-low bleed for improved LC/MS compatibility

• Compatible with both MeOH and MeCN mobile phases
• Rapid column equilibration without memory effects

4.  Preparative dimensions available

• Reproducible scale up from analytical separations
• Exploit increased loading capacity at elevated pH

ACE SuperC18 columns are an ideal choice for method development offering excellent column lifetime for reduced analysis cost. For further information on ACE SuperC18 contact your local ACE distributor, email: info@ace-hplc.com or www.ace-hplc.com