Next Generation Ion Trap and Orbitrap Mass Spectrometers

Thermo Fisher Scientific, Inc launched two new mass spectrometers at ASMS 2009, the Thermo Scientific LTQ Velos and LTQ Orbitrap Velos. The LTQ Velos™ features a new dual-pressure trap and advanced ion optics,
making it the world’s fastest and most sensitive ion trap mass spectrometer. The unique dual-pressure trap technology features two discrete pressure regions that allow the decoupling of ion manipulation and detection. This enables the use of optimal pressures during analysis, increasing both scan speed and resolution. The outstanding data quality and sensitivity of the LTQ Velos make it ideal for the analysis of complex mixtures, such as the identification of low level proteins and structural elucidation of metabolites in biological matrices.

The LTQ Velos can be upgraded to the LTQ Orbitrap Velos, allowing laboratories to extend their initial investment to include accurate mass and ultra-high resolution capabilities with no compromise to sensitivity and speed of analysis. The LTQ Orbitrap Velos™ combines the industry leading Orbitrap™ mass analyser, a new Higher-Energy Collisional Dissociation (HCD) cell and dual-pressure trap technology to routinely deliver ultra-high resolution and accurate-mass data. With new features, Thermo Scientific LTQ Orbitrap technology remains the most comprehensive structural identification mass spectrometry instrument and the platform of choice for the most confident protein and metabolite identification, characterisation and quantitation. The speed of the LTQ Velos-based mass spectrometers is ideal for coupling to U-HPLC systems, enabling researchers to identify more compounds in less time. “The new dualpressure trap and advanced ion optics combine to deliver increased sensitivity, improved ion transmission, and more efficient trapping and fragmentation of ions,” said Iain Mylchreest, Vice President of Mass Spectrometry for Thermo Fisher Scientific. “These major enhancements result in the fastest and most sensitive ion trap and Orbitrap mass spectrometers for any application involving complex mixtures.”