Multiply your Capabilities – More Automation Flexibility with Agilent Quick-Change Valves

Agilent offers a wide range of tools and solutions for automation of virtually any liquid chromatography application. Whether you need to increase sample throughput, accelerate method development, automate sample preparation, or solve any other challenging UHPLC application, the new Agilent 1200 Infinity Series Quick-Change Valves gives you utmost automation flexibility.

More Choice
Agilent Quick-Change Valves are available in stainless steel for high-pressure and ultrahigh pressure applications (600 and 1200 bar) as well as with bio-inert materials in the flow paths for bio-chromatographic applications. You can choose between externally-mounted valves or valve-containing modules of the Agilent 1200 Infinity Series such as the 1290 Infinity Thermostatted Column Compartment.

Higher Throughput and Faster Method Scouting
Designed with separate valve heads and drives, the Agilent Quick-Change Valves make it easy to mix and match configurations to meet individual application demands. The following two examples are just a glimpse of what is possible.

Efficient Sample Cleanup Using a 2-Position/6-Port Valve
Sample cleanup is essential for samples with complex matrices such as biological fluids, food extracts or wastewater. Before injection into an LC or LC/MS system, the analytes of interest must be separated from the sample matrix. Stripping methods for sample cleanup deal with analytes and matrices in the opposite way to enrichment methods – while the matrix is retained on a precolumn, the analytes are flushed through to the separation column.

Step 1: Matrix components are retained on a precolumn while the analytes
pass through to the analytical column for separation.

Step 2: After sample cleanup or matrix stripping, the precolumn is flushed in reversed
flow direction by the second pump.

Column Selection for Faster Method Scouting
To develop an appropriate LC method and determine the optimum separation conditions – for example, for chiral screening – samples must be analysed on several stationary phases. This process can be accelerated significantly using a 6-position/14-port valve that gives you automated access to up to six columns.

Using two 8-position/9-port valves mounted in two, stacked 1290 Infinity Thermostatted Column Compartments speeds up the process further with access to up to eight columns. Combination with further switching valves for solvent selection provides a comprehensive solution for automated method development.

Select from up to eight columns using two 8-position/9-port valves housed in two column compartments.

Learn more about the Agilent 1200 Infinity Quick-Change Valves. Watch video to see how it works at  www.agilent.com/chem/infinity-valve