Microscopy & Microtechniques
Supporting Cancer Drug Delivery Safety
May 30 2012
The new FlowCAM® PV Series imaging particle analysis system from laboratory instrumentation manufacturer Fluid Imaging Technologies automatically takes high-resolution, digital images of individual particles of encapsulated Paclitaxel to detect the presence of aggregates in the cancer treatment formulation and permit testing and assessment of drug delivery carriers and methods such as intravenous drip, emulsion, liposome and microsphere. Invaluable for documenting the safety of Paclitaxel in parenterals and for monitoring particulates in coatings on stents, catheters and other medical devices, the FlowCAM reveals both the Paclitaxel and its carrier in full colour and measures each particle based on the actual size and shape as imaged. The particles are characterised in real-time with up to 32 different parameters including advanced morphological properties such as perimeter, roughness, elongation and compactness, along with a host of traditional properties such as size, length, aspect ratio and ESD.
Detecting thousands of particles in a sample in less than a minute, the FlowCAM PV-40 and FlowCAM PV-100 Particle Vision series particle analysers save the images and corresponding data with a cGMP date and time stamp as tiff or jpeg files for easy review and emailing to colleagues. The FlowCAM biopharmaceutical instrumentation excels at detecting particles ranging from 2μm to 800μm in size even with samples as small as .1ml. Paclitaxel is also sold as Taxol, Abraxane®, Apo-Paclitaxel®, Aclixel, Asotax, Bristaxol, Bryoxet and Praxel.
Digital Edition
International Labmate Buyers' Guide 2024/25
June 2024
Buyers' Guide featuring: Product Listings & Manufacturers Directory Chromatography Articles - Enhancing HPLC Field Service with fast-response, non-invasive flowmeters - Digital transformatio...
View all digital editions
Events
Jul 03 2024 Gandhinagar, India
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa
Jul 28 2024 San Diego, CA USA