Liquid Chromatography
New Accurate-Mass TOF and Q-TOF LC/MS Provide Unmatched Performance
Apr 22 2008
Mass time-of-flight (TOF) and 6520 Accurate-Mass quadrupole time-offlight (Q-TOF) liquid chromatography/mass spectrometry (LC/MS) systems, delivering unmatched mass accuracy, mass resolution, sensitivity and speed for proteomics, metabolomics, product degradation and other complex experiments.
The new 6220 TOF and 6520 Q-TOF have added proprietary 32 Gbit/second highspeed data acquisition electronics that dramatically improve mass resolution to 20,000.
Additionally, the new products incorporate proprietary dual-gain analog to digital (ADC) time-of-flight electronics for a tenfold improvement of dynamic range - now approaching up to five orders of magnitude. The new Agilent 6520 Q-TOF has industry-leading performance in the following categories: attomole sensitivity; better than 2-ppm MS mass accuracy - approaching FTMS mass accuracy; better than 5-ppm
MS/MS mass accuracy - much better than FTMS mass accuracy at fast spectral acquisition rate; Tenfold improvement in in-spectra dynamic range without loss of sensitivity; mass resolution to 20,000 - not dependent on spectral acquisition rate; fast data acquisition ( ¡à 10 MS/MS spectra/sec) compatible with fast LC chromatography; and broad mass range from m/z 25 to 20,000.
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