• ChroZen USP 467 Player, All about residual solvent analysis
  • ChroZen USP 467 Player, All about residual solvent analysis

Laboratory products

ChroZen USP 467 Player, All about residual solvent analysis

ChroZen USP 467 Player is the optimised system for determination of residual solvents by fully complying with USP 467 and verifies the validity of analysis results for each analysis method.

For pharmacopeial purposes, residual solvents in pharmaceuticals are defined as organic volatile chemicals that are used or produced in the manufacture of drug substances or excipients, or in the preparation of drug products. Because these solvents can be harmful to human body if they remain in the final products, it is required to regulate these compounds not to exceed the specific limits defined in certain regulations.

United Stated Pharmacopeia (USP) classifies the residual solvents into Class â… , Class â…¡ and Class â…¢ depending on their risk to human health and USP 467 test method describes all the requirements for the analysis of residual solvents.

In this study, the determination of residual solvents (Class 1 & 2) in pharmaceutical products by ChroZen GC/FID with Headspace was conducted according to the method (Procedure A) specified in USP 467.

All of 5 compounds in Class 1 mixture had the S/N higher than 3 and 1,1,1-trichloroethane’s S/N was higher than 5. Moreover, the resolution of acetonitrile and methylene chloride was 2.48, which proves all are satisfied with the requirements.

YoungIn Chromass provides one stop solution for various dedicated applications and you only need to let us know what to analyse, and then every single component that is required to analyse your sample will be configured right away.

ChroZen USP 467 Player

Total Dream Solution includes:

  1. 1. Smart Hardware Platform (Based on ChroZen GC)
  2. 2. Smart ChroZen PAL 3 Series â…¡
  3. 3. Smart Software Control (Chromatography Data System) with Method Setup
  4. 4. All Related Consumables and Accessories
  5. 5. The Real Plug & Play Solution
  • QC Report according to the specified application
  • Method Set-Up & File Embedded
  • Specified Easy Manual
  1. 6. Columns - 624MS Column
  • : midpolarity Crossbond phase fused silica 30 m x 0.32 mm x 1.80 μm

Digital Edition

Lab Asia 32.1 Feb 2025

February 2025

Chromatography Articles - Comparing volumetric and thermal flowmeters for assessing and validating liquid chromatography performance Mass Spectrometry & Spectroscopy Articles - The importa...

View all digital editions

Events

SPS Smart Production Solutions Guangzhou

Feb 25 2025 Guanghzou, China

SmartLab Exchange

Feb 25 2025 Amsterdam, Netherlands

Nepal Lab

Feb 27 2025 Kathmandu, Nepal

PITTCON 2025

Mar 01 2025 Boston, MA, USA

IFPAC 2025

Mar 02 2025 Bethesda, MD, USA

View all events

Redirecting you now.
Labmate Awards Nominations - Open
The Labmate Awards for Excellence 2025 seek to recognise innovation, quality and achievement wherever it occurs within the laboratory sector. Launching this year the Labmate Awards for Excellence 2025 will have eleven voting categories chosen to reflect the broad range of noteworthy contributions that have been made across our industry in the past 12 months. Nominate your company Now.