Laboratory Products
Helping to Speed Up Clinical Studies of Pneumococcal Vaccines
Jan 30 2008
Scientists in the Immunobiology Unit at ICH are running clinical trials in which
children are vaccinated with new types of pneumococcal vaccines. Blood samples
from the children are subjected to an in vitro opsonophagocytic-killing assay
(OPKA) and the surviving Streptococcus pneumoniae are plated onto Todd-Hewitt
agar plates with yeast extract and an agar overlay containing antibiotics and a dye,
2, 3, 5-triphenyl tetrazolium chloride. The resulting red bacterial colonies are
counted using a customised ProtoCOL with a high resolution camera, to rapidly
determine the effectiveness of each vaccine.
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ILM 49.5 July
July 2024
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